Natural kratom comes from the mitragyna speciosa, a tropical evergreen tree in the coffee family native to Southeast Asia whose leaves have been used for centuries as an herbal supplement in traditional medicines.

Kratom is not a drug. Kratom is not an opiate. Kratom is not a synthetic substance. Naturally occurring Kratom is a safe herbal supplement that behaves as a partial mu-opioid receptor agonist and is used for pain management, energy, even depression and anxiety that are common among Americans. Kratom contains no opiates, but it does bind to the same receptor sites in the brain. Chocolate, coffee, exercise and even human breast milk hit these receptor sites in a similar fashion.

Emerging Science:

Effects of kratom on driving

Updated 8-Factor Analysis

Policy Briefs and Congressional Involvement

FDA tells Federal Court it has “not yet determined if kratom is dangerous.”
FDA Deputy Commissioner Signals Significant Shift
FDA completes a kratom “dose finding study”
CongressmanJack Bergman: “Let’s prevent the feds from jeopardizing veteran addiction recovery”
Congressman Jack Bergman letter

Watch Congressional Briefing on Kratom Science

Leading Edge Kratom Science - 2021 study
John hopkins survey study
Kratom Science Update: Evidence-Based Facts
Statement on the science of kratom products and their US regulation
Respiratory effects of oral mitragynine and oxycodone in a rodent model
School of Pharmacy, Concordia University Wisconsin Eight-Factor Analysis of Kratom
Twitter Exchange Between Former FDA Commissioner Scott Gottlieb and Former HHS Assistant Secretary for Health Brett Giroir
HHS Withdrawal Letter Dr. Giroir


policy briefs

The FDA Bias Against Dietary Supplements and Botanicals (and Kratom)
The FDA Negative “Feedback Loop” on Kratom Disinformation?
What Is Kratom?
Kratom is a Food
Why Should States Enact the KCPA?
Is Kratom Safe?
The Human and Economic Impacts of the Kratom Industry in the United States
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